Drug-Drug Interactions, Second Edition (Drugs and the Pharmaceutical Sciences)
A. David Rodrigues
Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives. Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on: key interplay between transporters and enzymes in drug metabolism and drug interactions the integral role of pharmacogenetics in metabolism-based drug-drug interactions in vivo – in vitro correlations (reversible, mechanism-based inhibition, induction) in silico approaches enabling structure-activity and structure-function studies high-throughput screening and GLP methods for evaluating drug interactions in vitro the use of transgenic animal models to evaluate drug interactions Providing helpful case examples and computer-aided modeling, Drug-Drug Interactions is filled with over 200 invaluable tables, equations, and figures to clarify key concepts, and incorporates critical new updated information.
Kateqoriyalar:
İl:
2007
Nəşr:
2
Nəşriyyat:
CRC Press
Dil:
english
Səhifələr:
768
ISBN 10:
0849375940
ISBN 13:
9780849375941
Fayl:
PDF, 6.61 MB
IPFS:
,
english, 2007